42
Termini:
Southwest segment
West: Broadford, Smyth County, JCT VA-91 (Saltville Highway, Veterans Rd.)
42

East: Poplar Hill, Giles County, JCT VA-100
42
Center segment
West: Newport, Giles County, JCT US-460 (Virginia Ave.)
42

East: New Castle, Craig County, JCT VA-311 (Salem Ave.)
42
Northeast segment
South: Longdale, Alleghany County, JCT VA-269 (Longdale Furnace Rd.)
42

North: Woodstock, Shenandoah County, JCT US-11 (Main St.)
42